Clinical cardiovascular Genetics

Consisting of contributions from experts in all specialties of cardiovascular
genetics and applied clinical cardiology, Principles and Practice of Clinical
Cardiovascular Genetics serves as the comprehensive volume for any clinician or resident in cardiology and genetics. Each chapter provides a detailed and
comprehensive account on the molecular genetics and clinical practice related to specific disorders or groups of disorders, including Marfan syndrome, thoracic and abdominal aortic aneurysms, hypertrophic, dilated and restrictive
cardiomyopathies and Arrhythmogenic right ventricular cardiomyopathy, as well as many others. All sections comprehensively address cardiovasuclar genetic disorders, beginning with an introduction and including separate sections on the disease’s basic biological aspects, specific genetic mechanisms or issues, clinical aspects, genetic management (e.g., genetic diagnosis, risk assessment, genetic counseling, genetic testing), and clinical management issues. The final section exclusively addresses the management of cardiovascular genetic disorders,
specifically considering stem cell therapy, genetic counseling, pharmacogenomics and the social and ethical issues surrounding disease treatment.


The Genome Clinic

Dedicated clinical service for individuals, patients & family members advising and supporting on all inherited medical and surgical conditions.
In addition, information and assistance provided on personalised genomic medical assessment and counselling. Please see the page ‘Services offered’ for further information.

Genetic & Genomic Meetings








First Cardiff International Genomics symposium-2009

Second Cardiff International Genomics symposium-2012



Genetic disorders among peoples from the Indian Subcontinent, Cardiff-2005

Challneges of genetic disorders in the Indian subcontinent, ICHG, Brisbaine-2006

Cardiovascula genetics in clinical practice, Bangalore, India-2010

Challenges of genetics & genomics in Medicine, Chennai, India-2011

Clinical Genetics & Genomic Medicine, New Delhi, India-2011

Genes and human malformations, Bangalore, India-2012

 Indian Cancer Genetics Conference, Mumbai, India-2013

 Current Trends in Genetic and Genomic Medicine, Lucknow, India-2013

 Next revolution in genetics & genomics, New Delhi, India-2013

Genomics & Global Health

A major comprehensive and classified resource of the current state of genomics in developing countries. Around 300 contributors from over 50 countries have written 123 chapters covering diverse areas from population strucutres, socio-cultural variation, genetic epidemiology, spectrum of inherited disorders, genetic counselling and ethical/social/legal aspects. The biotechnology and economic aspects of genomic applications are highlighted. See section on ‘Books’.

Professional Links

Professor Dhavendra Kumar has professional links with the following organizations:

 World Health Organization

  • Advisor on Birth Defects surveillance project for WHO South East Asia Regional Office
  • Member of the Advisory panel for the WHO Grand Challenges programme for Genomics in Developing world


 Human Genome Organization (International)

  • Member of the HUGO Council
  • Founding Editor for ‘The HUGO Journal’
  • Member of the HUGO Publications committee
  • Advisor to the HUGO Education programme


TheAmerican College of Medical Genetics


The British Society of Human Genetics


The Indian Society of Human Genetics


The Indian Academy of Medical Genetics


Association for Inherited Cardiac Conditions


Genomics and Clinical Medicine

An important milestone in medicine has been the recent completion of the Human Genome Project. The identification of 30,000 genes and their regulatory proteins provides the framework for understanding the metabolic basis of disease. This advance has also laid the foundation for a broad range of genomic tools that have opened the way for targeted genetic testing in a number of medical disorders. This book is designed to be the first major text to discuss genomics-based advances in disease susceptibility, diagnosis, prognostication, and prediction of treatment outcomes in various areas of medicine. After building a strong underpinning in the basic concepts of genomics, the authors of this book, all leaders in the field, proceed to discuss a wide range of clinical areas and the applications now afforded by genomic analysis.